Protein Purification
MilliporeSigma™ Calbiochem™ Pifithrin-α
A cell-permeable chemical inhibitor of p53.
MilliporeSigma™ Calbiochem™ PKR Inhibitor, Negative Control
The PKR Inhibitor, Negative Control, also referenced under CAS 852547-30-9, controls the biological activity of PKR. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
Cytiva HiTrap Protein L, 5 x 5ml
Prepacked with Capto L. Cytiva HiTrap Protein L, 5 x 5ml facilitate easy protein purification. They are prefilled with Capto L, a BioProcess chromatography medium that combines a rigid, high-flow agarose matrix with the immunoglobulin-binding recombinant protein, L ligand.
MilliporeSigma™ Calbiochem™ Tankyrase 1/2 Inhibitor VI, G007-LK
Tankyrase 1/2 Inhibitor VI, G007-LK, CAS 1380672-07-0, is a cell-permeable, potent and highly selective inhibitor of tankyrase (IC50 = 33 and 26nM for TNKS1 and TNKS2, respectively).
Cytiva HiLoad™ Superdex™ 75 pg
For high resolution preparative gel filtration chromatography with short run times and good recovery. Cytiva Lifescience™ HiLoad™ Superdex™ 75 pg are prepacked XK columns.
MilliporeSigma™ Calbiochem™ ERK Inhibitor VIII
A cell-permeable pyrimidylpyrrole compound that acts as an active site-targeting, highly potent and selective ERK1/2 inhibitor ( K I <2nM against Erk2; [ATP] = 65μM), while inhibiting GSK-3, Aurora A, Cdk2 only at much higher concentrations ( K I = 395, 540, and 852 nM, respectively) and exhibiting much reduced or little potency toward a panel of more than 130 other kinases ( K
MilliporeSigma™ Calbiochem™ Cathepsin L Inhibitor II
The Cathepsin L Inhibitor II controls the biological activity of Cathepsin L. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
Cytiva HiScreen Capto Blue
Excellent for method optimization and parameter screening due to the 10 cm bed height
MilliporeSigma™ Calbiochem™ NF-κB SN50, Cell-Permeable Inhibitor Peptide
NF-κB SN50, CAS 213546-43-3, is a cell-permeable peptide that contains the NLS sequence of NF-κB p50 linked to the hydrophobic region of K-FGF. Inhibits translocation of the NF-κB into the nucleus.
MilliporeSigma™ Calbiochem™ PIP3 Antagonist II, DM-PIT-1
The PIP3 Antagonist II, DM-PIT-1, also referenced under CAS 701947-53-7, controls the biological activity of PIP3.
MilliporeSigma™ Calbiochem™ Swainsonine, Swainsona canescens
Reversible active-site inhibitor of lysosomal α-mannosidase.
MilliporeSigma™ Calbiochem™ LIM Kinase Inhibitor I, LIMKi 3
The LIM Kinase Inhibitor I, LIMKi 3 controls the biological activity of LIM Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Hydroxyfasudil
A cell-permeable, hydroxylated metabolite of HA 1077 that displays anti-anginal properties.
MilliporeSigma™ Calbiochem™ HIF Inhibitor VII
A cell-permeable benzoxadiazolamine that prevents HIF-2α-HIF-β/ARNT heterodimeration by perturbing HIF-2α Per-ARNT-Sim/PAS-B domain surface β-sheet conformation via a 1:1 stoichiometric binding ( K D = 81nM), while exhibiting no affinity toward HIF-1αPAS-B
Thermo Scientific™ Pierce™ Direct Magnetic IP/Co-IP Kit
Conjugate any antibody or protein to magnetic beads and immunoprecipitate (affinity purify) target protein complexes without IP-antibody interference.